HOJAS SECAS DE MORERA COMO TÉ, NUEVO PRODUCTO NATURAL CUBANO.
Sirley González Laime
Detección de Orthotospovirus en un área suburbana de producción de hortalizas
Interacción in vitro entre hongos entomopatógenos biocontroladores de insectos plaga
Rolisbel Alfonso de la Cruz
Disposición espacial y predicción de la dispersión de Myzus persicae (Sulzer) (Insecta: Hemiptera: Aphididae) en Solanum tuberosum L
Lázaro Cuellar Yanes
DETECTION OF blaCTX-M-15, blaCTX-M-55 AND blaCMY-2 GENES HARBORING ESCHERICHIA COLI ISOLATED FROM FOOD-PRODUCING ANIMALS IN CUBA
Yanet Lopez Dorta
Desarrollo de un nanosensor colorimétrico para la detección de micoplasmas en vacunas veterinarias y productos biotecnológicos
Camilo Hernández Bertot
DETERMINACIÓN DEL POTENCIAL DE PRODUCCIÓN DE BIOGÁS EN EXCRETAS PORCINAS A PARTIR DE UNA ALIMENTACIÓN NO CONVENCIONAL.
Meylen Espina Nápoles
VERIFICACIÓN CONTINUA DEL PROCESO DE FABRICACIÓN DEL INGREDIENTE FARMACÉUTICO ACTIVO DE SURFACEN®
Estudio de parametros hematologicos y bioquimicos de cerdos en ceba suplementados con ractopamina
Yaneris Cabrera Otaño
Ensilaje de Morera sin la utilización de aditivos
Dariel Palenzuela González
Evento IV Seminario Internacional de Sanidad Agropecuaria starts on 8 de mayo de 2023, 8:00:00 -0400
Estimating evolutionary changes between highly passaged and original parental lumpy skin disease virus strains
(1 hora 30 minutos)
Research into the phylogenetic relationships of lumpy skin disease virus (LSDV) strains was long overlooked, partially due to its original restricted distribution to sub-Saharan Africa. However, recent incursions into northern latitudes, and a rapid spread causing major economic losses worldwide, have intensified additional research on the disease and the causative virus. This study delineates the phylogeny of LSDV in the context of full genome sequences of strains recovered in the field, as well as strains highly passaged in cell culture. We sequenced the oldest known field strain to date (isolate LSDV/Haden/RSA/1954 [South Africa] recovered from an outbreak in 1954), a recent field isolate (LSDV/280-KZN/RSA/2018 [South Africa] sequenced directly from blood during an outbreak in 2018) and strain LSDV/Russia/Dagestan-75 (a high-passaged cell culture strain derived from the field strain, LSDV/Russia/Dagestan/2015 [Russia]). Sequence analysis placed the field strain LSDV/Haden/RSA/1954 in the same cluster (cluster 1.1) with attenuated Neethling-type commercial vaccine viruses, with eight SNP differences, discrediting the previously held hypothesis that cluster 1.1 vaccine strains were derived from cluster 1.2 field viruses via the process of attenuation between them. In contrast, the recent LSDV/280-KZN/RSA/2018 isolate grouped with other recent field isolates in cluster 1.2, providing evidence that cluster 1.1 strains were displaced by cluster 1.2 strains in South Africa. Based on the field isolates between 1954 and 2018, the substitution rate of 7.4 × 10-6 substitutions/site/year was established, with mutations occurring in either synonymous sites or intergenic regions. This is the first evolutionary metric recorded for LSDV. Comparing the genome sequences of high-passage strains of LSDV showed that propagation in vitro without animal host selective pressure generates mainly non-synonymous SNPs in virus-replication genes. These results improve our understanding of LSDV evolution and demonstrate that the population dynamics of circulating isolates is not constant, with LSDV associated with different genetic clusters dominating the landscape during specific periods in time.